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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68542
Species: Mus musculus
RGD Object: Gene
Symbol: Dpys
Name: dihydropyrimidinase
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dpysdecreases expressionISODpys (Rattus norvegicus)6480464CTDDiethylnitrosamine results in decreased expression of DPYS mRNAPMID:19638242
Dpysmultiple interactionsISODpys (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DPYS mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DPYS mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of DPYS mRNAPMID:17602206 PMID:20360939 PMID:28943392
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