GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MTOR | affects methylation | EXP | | 6480464 | CTD | Arsenic affects the methylation of MTOR gene | PMID:25304211 | MTOR | increases expression | EXP | | 6480464 | CTD | Arsenic results in increased expression of MTOR protein; Arsenic results in increased expression of MTOR protein modified form | PMID:25586904 PMID:29248574 | MTOR | multiple interactions | EXP | | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein; OSGIN1 protein promotes the reaction [Arsenic results in increased expression of MTOR protein modified form]; Sirolimus inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein]; UCA1 mRNA promotes the reaction [Arsenic results in increased expression of MTOR protein modified form]; Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein] | PMID:29248574 PMID:32802178 | |
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