GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MTOR | affects methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene affects the methylation of MTOR promoter | PMID:27901495 | MTOR | multiple interactions | EXP | | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein; Sirolimus inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein]; Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of MTOR protein] | PMID:32802178 | MTOR | decreases methylation | ISO | Mtor (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of MTOR intron | PMID:27901495 | MTOR | multiple interactions | ISO | Mtor (Mus musculus) | 6480464 | CTD | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of MTOR mRNA] | PMID:22228805 | |
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