GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lrat | multiple interactions | EXP | | 6480464 | CTD | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of LRAT mRNA; [Vitamin A co-treated with Tetrachlorodibenzodioxin] results in increased expression of LRAT mRNA; Tetrachlorodibenzodioxin inhibits the reaction [Vitamin A results in increased expression of LRAT mRNA] | PMID:16292751 PMID:25975270 | Lrat | affects expression | ISO | Lrat (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of LRAT mRNA | PMID:22298810 | Lrat | increases activity | ISO | Lrat (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased activity of LRAT protein | PMID:11097864 | Lrat | increases expression | ISO | Lrat (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of LRAT mRNA | PMID:12606150 PMID:21215274 PMID:32109520 | Lrat | multiple interactions | ISO | Lrat (Rattus norvegicus) | 6480464 | CTD | [Tetrachlorodibenzodioxin results in increased activity of LRAT protein] which results in increased chemical synthesis of Tretinoin | PMID:11097864 | | ||||||||||||||||||||||
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