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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68469
Species: Mus musculus
RGD Object: Gene
Symbol: Por
Name: cytochrome p450 oxidoreductase
Acc ID: CHEBI:77013
Term: beta-naphthoflavone
Definition: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
Chemical ID: MESH:D019324
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pormultiple interactionsEXP 6480464CTD[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of POR mRNAPMID:19737545
Pormultiple interactionsISOPor (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of POR mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of POR mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of POR proteinPMID:18164116 PMID:21295105 PMID:30842367
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