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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68433
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aqp9
Name: aquaporin 9
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aqp9decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of AQP9 mRNAPMID:19490992 PMID:21215274 PMID:21724226
Aqp9affects expressionISOAqp9 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of AQP9 mRNAPMID:21570461
Aqp9decreases expressionISOAQP9 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of AQP9 mRNAPMID:20106945 PMID:26159488
Aqp9increases expressionISOAqp9 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of AQP9 mRNAPMID:18796159
Aqp9multiple interactionsISOAQP9 (Homo sapiens)6480464CTD[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AQP9 mRNAPMID:26159488
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