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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:3684
Term: chrysin 5,7-dimethyl ether
Definition: A dimethoxyflavone that is the 5,7-dimethyl ether derivative of chrysin.
Chemical ID: MESH:C060298
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD5, 7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA], 5, 7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]

PMID:21554863
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.