GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | decreases expression | EXP | | 6480464 | CTD | Zinc results in decreased expression of CCND1 mRNA | PMID:17074742 | Ccnd1 | decreases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Zinc deficiency results in decreased expression of CCND1 protein; Zinc results in decreased expression of CCND1 protein | PMID:19913001 PMID:21600978 | Ccnd1 | increases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Zinc results in increased expression of CCND1 mRNA | PMID:19071009 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of CCND1 protein]; Thioctic Acid inhibits the reaction [Zinc deficiency results in decreased expression of CCND1 protein] | PMID:21600978 | Ccnd1 | multiple interactions | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | [Rutin binds to Zinc] which results in decreased expression of CCND1 mRNA; PTGS2 gene mutant form promotes the reaction [Zinc deficiency results in increased expression of CCND1 protein]; Zinc inhibits the reaction [PTGS2 gene mutant form promotes the reaction [Zinc deficiency results in increased expression of CCND1 protein]] | PMID:20857495 PMID:26091902 | |
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