GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | decreases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of CCND1 mRNA | PMID:19224547 PMID:31150632 | Ccnd1 | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of CCND1 mRNA; Carbon Tetrachloride results in increased expression of CCND1 protein | PMID:17298859 PMID:27818223 PMID:30723492 | Ccnd1 | multiple interactions | EXP | | 6480464 | CTD | hesperetin analog inhibits the reaction [Carbon Tetrachloride results in increased expression of CCND1 protein] | PMID:27818223 | Ccnd1 | decreases expression | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of CCND1 mRNA | PMID:17484886 | Ccnd1 | increases expression | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of CCND1 mRNA; Carbon Tetrachloride results in increased expression of CCND1 protein | PMID:12730884 PMID:14999682 PMID:15056808 PMID:19393728 PMID:19887370 PMID:25747392 PMID:27339419 PMID:29535048 PMID:31816328 PMID:31919559 | Ccnd1 | multiple interactions | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | [PANX1 protein co-treated with Carbon Tetrachloride] affects the expression of CCND1 mRNA; alisol B 23-acetate promotes the reaction [Carbon Tetrachloride results in increased expression of CCND1 mRNA]; alisol B 23-acetate promotes the reaction [Carbon Tetrachloride results in increased expression of CCND1 protein]; Chenodeoxycholic Acid promotes the reaction [Carbon Tetrachloride results in increased expression of CCND1 mRNA]; GANT 61 inhibits the reaction [Carbon Tetrachloride results in increased expression of CCND1 mRNA]; GANT 61 inhibits the reaction [Carbon Tetrachloride results in increased expression of CCND1 protein]; IL6 protein affects the reaction [Carbon Tetrachloride results in increased expression of CCND1 protein]; LEP protein affects the reaction [Carbon Tetrachloride results in increased expression of CCND1 protein]; OSM protein affects the reaction [IL6 protein affects the reaction [Carbon Tetrachloride results in increased expression of CCND1 protein]]; PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CCND1 mRNA] | PMID:12730884 PMID:14999682 PMID:18038451 PMID:25747392 PMID:29987408 PMID:31816328 | | ||||||||||||||||||||||
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