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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68367
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pts
Name: 6-pyruvoyl-tetrahydropterin synthase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptsdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PTS mRNAPMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
Ptsincreases expressionEXP 6480464CTDbisphenol A results in increased expression of PTS mRNAPMID:32145629
Ptsmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PTS mRNAPMID:36041667
Ptsdecreases expressionISOPTS (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PTS mRNA; bisphenol A results in decreased expression of PTS proteinPMID:29275510 PMID:33376534
Ptsincreases expressionISOPts (Mus musculus)6480464CTDbisphenol A results in increased expression of PTS mRNAPMID:33221593
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