GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Htt | multiple interactions | EXP | | 6480464 | CTD | Manganese results in decreased phosphorylation of and results in increased expression of HTT protein | PMID:25099302 | Htt | decreases abundance | ISO | Htt (Mus musculus) | 6480464 | CTD | HTT gene mutant form results in decreased abundance of Manganese | PMID:19845833 | Htt | decreases response to substance | ISO | Htt (Mus musculus) | 6480464 | CTD | HTT gene mutant form results in decreased susceptibility to Manganese | PMID:19845833 | Htt | decreases uptake | ISO | Htt (Mus musculus) | 6480464 | CTD | HTT protein mutant form results in decreased uptake of Manganese | PMID:20547568 | Htt | multiple interactions | ISO | Htt (Mus musculus) | 6480464 | CTD | HTT protein mutant form inhibits the reaction [Manganese results in decreased expression of UBQLN1 protein]; HTT protein mutant form inhibits the reaction [Manganese results in increased expression of NEFL protein]; Manganese inhibits the reaction [HTT protein mutant form affects the expression of SAE1 protein] | PMID:22191580 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |