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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68335
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Por
Name: cytochrome p450 oxidoreductase
Acc ID: CHEBI:254496
Term: 7,12-dimethyltetraphene
Definition: A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke.
Chemical ID: MESH:D015127
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pordecreases abundanceISOPor (Mus musculus)6480464CTDPOR protein results in decreased abundance of 9,10-Dimethyl-1,2-benzanthracenePMID:22595614
Pormultiple interactionsISOPor (Mus musculus)6480464CTDPOR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]PMID:22595614
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