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GENE - TERM ANNOTATION REPORT

RGD ID: 67383
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkcd
Name: protein kinase C, delta
Acc ID: GO:0043560
Term: insulin receptor substrate binding
Definition: Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.
Definition Source(s): PMID:12829233
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PrkcdenablesISOPrkcd (Mus musculus)1624291RGDUniProtKB:P35570 MGI:3836105 PMID:18285345

MGI:3836105 PMID:18285345
PrkcdenablesIEAUniProtKB:P28867 or ensembl:ENSMUSP000001078301600115EnsemblGO_REF:0000107

GO_REF:0000107
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