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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 632286
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a8
Name: solute carrier family 22 member 8
Acc ID: CHEBI:43355
Term: indoxyl sulfate
Definition: An aryl sulfate that is indoxyl in which the hydroxyl hydrogen is substituted by a sulfo group.
Chemical ID: MESH:D007200
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a8multiple interactionsISOSLC22A8 (Homo sapiens)6480464CTD[Lansoprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican; [Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican; [Pantoprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of IndicanPMID:36243147
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