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GENE - TERM ANNOTATION REPORT

RGD ID: 631418
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ncstn
Name: nicastrin
Acc ID: GO:1990926
Term: short-term synaptic potentiation
Definition: The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds.
Definition Source(s): GOC:dos, GOC:sp, ISBN:9780071120005, PMID:11826273, PMID:26738595
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ncstnacts_upstream_of_or_withinISONcstn (Mus musculus)1624291RGDMGI:3796837 PMID:24889619

PMID:24889619
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