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GENE - TERM ANNOTATION REPORT

RGD ID: 631418
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ncstn
Name: nicastrin
Acc ID: GO:0022010
Term: central nervous system myelination
Definition: The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
Definition Source(s): GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ncstnacts_upstream_of_or_withinISONcstn (Mus musculus)1624291RGDMGI:3796837 PMID:27008863

PMID:27008863
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