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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631362
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapkapk2
Name: MAPK activated protein kinase 2
Acc ID: CHEBI:17712
Term: 9H-xanthine
Definition: An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Chemical ID: MESH:D019820
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapkapk2multiple interactionsEXP 6480464CTD3,4-dihydroxyphenylethanol inhibits the reaction [[Xanthine co-treated with XDH protein] results in increased phosphorylation of MAPKAPK2 protein]; [Xanthine co-treated with XDH protein] results in increased phosphorylation of MAPKAPK2 protein; Quercetin inhibits the reaction [[Xanthine co-treated with XDH protein] results in increased phosphorylation of MAPKAPK2 protein]PMID:26374991
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