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GENE - TERM ANNOTATION REPORT

RGD ID: 631352
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlr9
Name: toll-like receptor 9
Acc ID: DOID:2986
Term: IgA glomerulonephritis
Definition: A glomerulonephritis characterized by build up of IgA antibody in the glomerulus. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/IgA_nephropathy "DO" "DO", http://www.nlm.nih.gov/medlineplus/ency/article/000466.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr9 ISOTlr9 (Mus musculus)7246893RGDassociated with Graft vs Host Disease; mRNA:increased expression:splenocyte (mouse) 
Tlr9severityISOTLR9 (Homo sapiens)7246889RGDDNA:SNPs:intron, exon:IVS4-44A>G, c.1635G>A (rs352139, rs352140) (human) 
Tlr9severityISOTlr9 (Mus musculus)7246889RGDDNA, mRNA:SNP, increased expression:exon, spleen:g.159C>G (mouse) 
Tlr9treatmentISOTlr9 (Mus musculus)7246893RGDassociated with Graft vs Host Disease 
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