GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tlr9 | multiple interactions | ISO | Tlr9 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]; Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased activity of NFKB1 protein]; Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased activity of RELA protein]; Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased expression of ITGAX protein]; Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased secretion of IL10 protein]; Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased secretion of IL6 protein]; Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased secretion of TNF protein]; Tetrachlorodibenzodioxin promotes the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased expression of CD86 protein]; Tetrachlorodibenzodioxin promotes the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] which results in increased expression of ICAM1 protein] | PMID:21097750 | | ||||||||||||||||||||||
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