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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631344
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abca1
Name: ATP binding cassette subfamily A member 1
Acc ID: CHEBI:28716
Term: (9Z)-hexadecenoic acid
Definition: A hexadecenoic acid with a cis-double bond at position C-9.
Chemical ID: MESH:C008757
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases degradationISORGD:7361576480464CTDpalmitoleic acid results in increased degradation of ABCA1 protein

PMID:16118212
increases phosphorylationISORGD:7361576480464CTDpalmitoleic acid results in increased phosphorylation of ABCA1 protein

PMID:16118212
multiple interactionsISORGD:7361576480464CTDpalmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]], palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]

PMID:16118212
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.