GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdk5r1 | affects splicing | ISO | Cdk5r1 (Mus musculus) | 6480464 | CTD | Ethanol affects the splicing of CDK5R1 mRNA | PMID:30319688 | Cdk5r1 | multiple interactions | ISO | Cdk5r1 (Mus musculus) | 6480464 | CTD | [Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein; CNR1 protein affects the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]; Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein] | PMID:30143782 | | ||||||||||||||||||||||
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