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GENE - TERM ANNOTATION REPORT

RGD ID: 628868
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itgb3
Name: integrin subunit beta 3
Acc ID: GO:0072378
Term: blood coagulation, fibrin clot formation
Definition: A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.
Definition Source(s): GOC:add, GOC:mah, GOC:pde
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgb3acts_upstream_of_or_withinISOItgb3 (Mus musculus)1624291RGDMGI:2175913 PMID:28576878

PMID:28576878
Itgb3involved_inIEAUniProtKB:O54890 or ensembl:ENSMUSP000000210281600115EnsemblGO_REF:0000107

GO_REF:0000107
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