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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628859
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tank
Name: TRAF family member-associated NFKB activator
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tankincreases expressionEXP 6480464CTDEstradiol results in increased expression of TANK mRNAPMID:17010207
Tankaffects expressionISOTANK (Homo sapiens)6480464CTDEstradiol affects the expression of TANK mRNAPMID:14699072
Tankmultiple interactionsISOTANK (Homo sapiens)6480464CTD[Estradiol binds to ESR2 protein] which results in increased expression of TANK mRNA; ESR2 protein affects the reaction [Estradiol results in increased expression of TANK mRNA]PMID:14699072 PMID:20404318
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