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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:641
Term: N-methyl-4-phenylpyridinium
Definition: A pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position.
Chemical ID: MESH:D015655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9increases activityISOMapk9 (Mus musculus)6480464CTD1-Methyl-4-phenylpyridinium results in increased activity of MAPK9 proteinPMID:11181820
Mapk9increases expressionISOMAPK9 (Homo sapiens)6480464CTD1-Methyl-4-phenylpyridinium results in increased expression of MAPK9 mRNAPMID:25234470
Mapk9increases phosphorylationISOMAPK9 (Homo sapiens)6480464CTD1-Methyl-4-phenylpyridinium results in increased phosphorylation of MAPK9 proteinPMID:20946892
Mapk9multiple interactionsISOMAPK9 (Homo sapiens)6480464CTD8-phenyl-6a,7,8,9,9a,10-hexahydro-6H-isoindolo(5,6-g)quinoxaline-7,9-dione inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of MAPK9 protein]PMID:20946892
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