Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9decreases methylationEXP 6480464CTDCadmium Chloride results in decreased methylation of MAPK9 promoterPMID:22457795
Mapk9increases phosphorylationEXP 6480464CTDCadmium Chloride results in increased phosphorylation of MAPK9 proteinPMID:23876460 PMID:31348969 PMID:35122928
Mapk9multiple interactionsEXP 6480464CTD1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK9 protein]; [Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK9 protein; Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein; Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; N(6),N(6)-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; pyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]PMID:15618353 PMID:20829427 PMID:21544200 PMID:31348969
Mapk9increases expressionISOMAPK9 (Homo sapiens)6480464CTDCadmium Chloride results in increased expression of MAPK9 protein modified formPMID:24419708
Mapk9increases phosphorylationISOMAPK9 (Homo sapiens)6480464CTDCadmium Chloride results in increased phosphorylation of MAPK9 proteinPMID:10874044 PMID:35122928
Mapk9increases phosphorylationISOMapk9 (Mus musculus)6480464CTDCadmium Chloride results in increased phosphorylation of MAPK9 proteinPMID:11958953
Mapk9multiple interactionsISOMAPK9 (Homo sapiens)6480464CTD1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of MAPK9 mRNA; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein; Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; KT 5823 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; tin protoporphyrin IX inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]PMID:12634122 PMID:21544200 PMID:35122928
Mapk9multiple interactionsISOMapk9 (Mus musculus)6480464CTD1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein; Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; LL Z1640-2 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; MAPK9 mutant form inhibits the reaction [Cadmium Chloride results in increased expression of HSPA1A protein]; MT1 affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; MT2 affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; Silymarin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]PMID:11958953 PMID:15081267 PMID:16728380 PMID:18348256 PMID:21544200
Go Back to source page   Continue to Ontology report