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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628841
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpv1
Name: transient receptor potential cation channel, subfamily V, member 1
Acc ID: CHEBI:27575
Term: adenosine 5'-[gamma-thio]triphosphate
Definition: A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.
Chemical ID: MESH:C022571
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpv1increases activityEXP 6480464CTDadenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 proteinPMID:11140687
Trpv1multiple interactionsEXP 6480464CTDCapsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]PMID:11140687
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