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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628827
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1d1
Name: nuclear receptor subfamily 1, group D, member 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1d1affects expressionEXP 6480464CTDbisphenol A affects the expression of NR1D1 mRNAPMID:30903817 PMID:32145629
Nr1d1increases expressionEXP 6480464CTDbisphenol A results in increased expression of NR1D1 mRNAPMID:25181051 PMID:35192832
Nr1d1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NR1D1 mRNAPMID:36041667
Nr1d1affects expressionISONR1D1 (Homo sapiens)6480464CTDbisphenol A affects the expression of NR1D1 mRNAPMID:30903817
Nr1d1decreases expressionISONr1d1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of NR1D1 mRNA; bisphenol A results in decreased expression of NR1D1 proteinPMID:33297044
Nr1d1increases expressionISONr1d1 (Mus musculus)6480464CTDbisphenol A results in increased expression of NR1D1 mRNAPMID:30500912 PMID:32156529
Nr1d1multiple interactionsISONr1d1 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of NR1D1 mRNA; SR9009 inhibits the reaction [bisphenol A results in decreased expression of NR1D1 protein]PMID:28433925 PMID:33297044
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