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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628748
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adipoq
Name: adiponectin, C1Q and collagen domain containing
Acc ID: CHEBI:64243
Term: monosodium L-glutamate
Definition: An optically active form of monosodium glutamate having L-configuration.
Chemical ID: MESH:D012970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adipoqdecreases expressionISOAdipoq (Mus musculus)6480464CTDSodium Glutamate results in decreased expression of ADIPOQ proteinPMID:21549692 PMID:32103741
Adipoqmultiple interactionsISOAdipoq (Mus musculus)6480464CTD[Sodium Glutamate co-treated with Pioglitazone] results in increased expression of ADIPOQ protein; [Sodium Glutamate co-treated with Plant Extracts] results in decreased expression of ADIPOQ mRNA; Bezafibrate inhibits the reaction [Sodium Glutamate results in decreased expression of ADIPOQ protein]; fructooligosaccharide inhibits the reaction [Sodium Glutamate results in decreased expression of ADIPOQ protein]PMID:21549692 PMID:27918843 PMID:32103741
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