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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628714
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd86
Name: CD86 molecule
Acc ID: CHEBI:5635
Term: helenalin
Definition: A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by a hydroxy group at position 4, methyl groups at positions 4a and 8 and a methylidene group at position 3 (the 3aS,4S,4aR,7aR,8R,9aR stereoisomer).
Chemical ID: MESH:C001329
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd86multiple interactionsISOCD86 (Homo sapiens)6480464CTDhelenalin inhibits the reaction [Drugs, Chinese Herbal results in increased expression of CD86 protein]; helenalin inhibits the reaction [Polysaccharides results in increased expression of CD86 protein]PMID:15894585
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