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GENE - TERM ANNOTATION REPORT

RGD ID: 628709
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a18
Name: cytochrome P450, family 3, subfamily a, polypeptide 18
Acc ID: GO:0050649
Term: testosterone 6-beta-hydroxylase activity
Definition: Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 6beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
Definition Source(s): PMID:11726664, RHEA:46296
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a18 IDA 727620RGD  
Cyp3a18enablesIBAPANTHER:PTN001548724 or Cyp3a23-3a1 (Rattus norvegicus) or Cyp3a18 (Rattus norvegicus) or Cyp3a2 (Rattus norvegicus) or UniProtKB:P08684 or UniProtKB:P244631600115GO_CentralGO_REF:0000033

GO_REF:0000033
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