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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628704
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il12b
Name: interleukin 12B
Acc ID: CHEBI:47807
Term: sulforaphane
Definition: An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Chemical ID: MESH:C016766
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il12bmultiple interactionsISOIL12B (Homo sapiens)6480464CTDNFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]; sulforaphane inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]PMID:16890772
Il12bmultiple interactionsISOIl12b (Mus musculus)6480464CTDsulforaphane inhibits the reaction [Trichloroethylene results in increased expression of IL12B mRNA]PMID:33930529
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