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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Brs3
Name: bombesin receptor subtype 3
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Brs3increases expressionISOBRS3 (Homo sapiens)6480464CTDOzone results in increased expression of BRS3 mRNAPMID:16426703 PMID:17355223
Brs3multiple interactionsISOBRS3 (Homo sapiens)6480464CTDOzone promotes the reaction [PPARA protein binds to BRS3 promoter]; Ozone promotes the reaction [TFAP2A protein binds to BRS3 promoter]; PPARA protein affects the reaction [Ozone results in increased expression of BRS3 mRNA]; TFAP2A protein affects the reaction [Ozone results in increased expression of BRS3 mRNA]PMID:17355223
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