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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628637
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pycard
Name: PYD and CARD domain containing
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pycardincreases expressionISOPycard (Mus musculus)6480464CTDDextran Sulfate results in increased expression of PYCARD mRNA; Dextran Sulfate results in increased expression of PYCARD proteinPMID:30270565 PMID:34964214
Pycardmultiple interactionsISOPycard (Mus musculus)6480464CTD[Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of PYCARD protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD protein]PMID:30270565 PMID:34964214
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