GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pycard | increases expression | ISO | Pycard (Mus musculus) | 6480464 | CTD | Homocysteine results in increased expression of PYCARD mRNA | PMID:22647887 | Pycard | multiple interactions | ISO | Pycard (Mus musculus) | 6480464 | CTD | [Folic Acid deficiency results in increased abundance of Homocysteine] promotes the reaction [NLRC3 protein binds to PYCARD protein binds to CASP1 protein]; CASP1 protein affects the reaction [Homocysteine promotes the reaction [NLRC3 protein binds to PYCARD protein binds to CASP1 protein]]; Homocysteine promotes the reaction [NLRC3 protein binds to PYCARD protein binds to CASP1 protein]; PYCARD protein affects the reaction [Homocysteine promotes the reaction [NLRC3 protein binds to PYCARD protein binds to CASP1 protein]]; PYCARD protein affects the reaction [Homocysteine results in decreased secretion of VEGFA protein]; PYCARD protein affects the reaction [Homocysteine results in increased activity of CASP1 protein] | PMID:22647887 | | ||||||||||||||||||||||
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