GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pycard | increases expression | EXP | | 6480464 | CTD | Cholesterol analog results in increased expression of PYCARD mRNA | PMID:19477266 | Pycard | multiple interactions | EXP | | 6480464 | CTD | [Cholesterol co-treated with Ergosterol] results in increased expression of PYCARD mRNA; [Cholesterol co-treated with Ergosterol] results in increased expression of PYCARD protein; resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of PYCARD mRNA]; resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of PYCARD protein] | PMID:25833014 | Pycard | affects localization | ISO | Pycard (Mus musculus) | 6480464 | CTD | Cholesterol analog affects the localization of PYCARD protein | PMID:28633109 | Pycard | multiple interactions | ISO | Pycard (Mus musculus) | 6480464 | CTD | [Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of PYCARD mRNA; Amitriptyline inhibits the reaction [Cholesterol analog affects the localization of PYCARD protein]; SMPD1 protein affects the reaction [Cholesterol analog affects the localization of PYCARD protein] | PMID:22129739 PMID:28633109 | | ||||||||||||||||||||||
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