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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a23-3a1
Name: cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
Acc ID: CHEBI:39421
Term: perfluorooctane-1-sulfonic acid
Definition: A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines.
Chemical ID: MESH:C076994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a23-3a1affects expressionEXP 6480464CTDperfluorooctane sulfonic acid affects the expression of CYP3A23-3A1 mRNAPMID:17383973
Cyp3a23-3a1increases expressionEXP 6480464CTDperfluorooctane sulfonic acid analog results in increased expression of CYP3A23-3A1 protein; perfluorooctane sulfonic acid results in increased expression of CYP3A23-3A1 mRNAPMID:18692542 PMID:19162173 PMID:21723365 PMID:22245121
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