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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:42567
Term: fisetin
Definition: A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'.
Chemical ID: MESH:C017875
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:691656480464CTDfisetin results in increased expression of DDIT3 protein

PMID:28181380
multiple interactionsISORGD:691656480464CTD1, 2-bis(2-aminophenoxy)ethane-N, N, N', N'-tetraacetic acid inhibits the reaction [fisetin results in increased expression of DDIT3 protein]

PMID:28181380
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.