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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of DDIT3 mRNA

PMID:30769081
multiple interactionsEXP 6480464CTD[Eicosapentaenoic Acid co-treated with methylmercuric chloride] results in increased expression of DDIT3 mRNA, Docosahexaenoic Acids promotes the reaction [methylmercuric chloride results in increased expression of DDIT3 mRNA], Eicosapentaenoic Acid inhibits the reaction [Docosahexaenoic Acids promotes the reaction [methylmercuric chloride results in increased expression of DDIT3 mRNA]]

PMID:30769081
increases expressionISORGD:691656480464CTDmethylmercuric chloride results in increased expression of DDIT3 mRNA

PMID:28001369
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.