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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62358
Species: Mus musculus
RGD Object: Gene
Symbol: Slc37a4
Name: solute carrier family 37 (glucose-6-phosphate transporter), member 4
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc37a4affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SLC37A4 mRNAPMID:21570461 PMID:26377647
Slc37a4decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC37A4 mRNAPMID:19770486
Slc37a4multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of SLC37A4 mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC37A4 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of SLC37A4 mRNAPMID:17942748 PMID:25975270 PMID:28433925
Slc37a4affects expressionISOSlc37a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC37A4 mRNAPMID:22298810
Slc37a4decreases expressionISOSlc37a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC37A4 mRNAPMID:16054898 PMID:18796159 PMID:19692669 PMID:20959002 PMID:21215274 PMID:21724226 PMID:22342509
Slc37a4increases expressionISOSlc37a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SLC37A4 mRNAPMID:33387578
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