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GENE - TERM ANNOTATION REPORT

RGD ID: 62288
Species: Mus musculus
RGD Object: Gene
Symbol: F2
Name: coagulation factor II
Acc ID: DOID:9007096
Term: Stroke
Definition: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Definition Source(s): MESH:D020521
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F2 ISOF2 (Homo sapiens)5147755RGD  
F2 ISOF2 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:15534175
F2 ISOF2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: CEREBROVASCULAR ACCIDENTPMID:10027711 PMID:10233438 PMID:10233439 PMID:10336270 PMID:10348710 PMID:10348711 PMID:10348712 PMID:10406905 PMID:10477778 PMID:10544935 PMID:11358905 PMID:11443298 PMID:11506076 PMID:11796466 PMID:11874997 PMID:11904676 PMID:15059842 PMID:15534175 PMID:16493002 PMID:16606808 PMID:19159930 PMID:19289024 PMID:19531787 PMID:19554541 PMID:19560233 PMID:19652888 PMID:20301327 PMID:21243428 PMID:21349849 PMID:2222810 PMID:23429074 PMID:24033266 PMID:2429850 PMID:25741868 PMID:27031503 PMID:2825773 PMID:28492532 PMID:28707429 PMID:30297698 PMID:34110897 PMID:34355501 PMID:6305407 PMID:8696333 PMID:8896550 PMID:8916933 PMID:9106528 PMID:9292507 PMID:9462220 PMID:9493607 PMID:9531249 PMID:9569177 PMID:9694698 PMID:9869612
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