GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | F2 | multiple interactions | EXP | | 6480464 | CTD | Heparin results in increased expression of [F2 protein binds to SERPINC1 protein] | PMID:16961586 | F2 | decreases expression | ISO | F2 (Homo sapiens) | 6480464 | CTD | Heparin results in decreased expression of F2 protein | PMID:11869846 | F2 | increases expression | ISO | F2 (Homo sapiens) | 6480464 | CTD | Heparin deficiency results in increased expression of F2 protein; Heparin results in increased expression of F2 protein | PMID:11869846 PMID:16391376 | F2 | multiple interactions | ISO | F2 (Homo sapiens) | 6480464 | CTD | F2 protein promotes the reaction [Heparin results in increased abundance of Nitric Oxide]; Heparin deficiency results in increased cleavage of and results in increased activity of F2 protein; Heparin deficiency results in increased expression of [SERPINC1 protein binds to F2 protein]; Heparin inhibits the reaction [F2 protein affects the localization of SELP protein]; Heparin inhibits the reaction [F2 protein results in increased cleavage of F2R protein]; Heparin inhibits the reaction [F2 protein results in increased expression of EDN1 mRNA]; Heparin inhibits the reaction [F2 protein results in increased secretion of EDN1 protein] | PMID:11869846 PMID:19468011 PMID:7509996 PMID:7895349 PMID:8408661 PMID:9740346 | | ||||||||||||||||||||||
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