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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62288
Species: Mus musculus
RGD Object: Gene
Symbol: F2
Name: coagulation factor II
Acc ID: CHEBI:18291
Term: manganese atom
Definition: A manganese group element atom that has formula Mn.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F2increases uptakeISOF2 (Homo sapiens)6480464CTDF2 protein results in increased uptake of ManganesePMID:2125206
F2multiple interactionsISOF2 (Homo sapiens)6480464CTD1-Methyl-3-isobutylxanthine inhibits the reaction [F2 protein results in increased uptake of Manganese]; Colforsin inhibits the reaction [F2 protein results in increased uptake of Manganese]; Nickel inhibits the reaction [F2 protein results in increased uptake of Manganese]; Tetradecanoylphorbol Acetate inhibits the reaction [F2 protein results in increased uptake of Manganese]PMID:2125206
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