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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62279
Species: Mus musculus
RGD Object: Gene
Symbol: Phgdh
Name: 3-phosphoglycerate dehydrogenase
Acc ID: CHEBI:81582
Term: 2,4-dibromophenyl 2,4,5-tribromophenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 4, 5, 2', and 4' positions have been replaced by bromines.
Chemical ID: MESH:C477694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTD2, 2', 4, 4', 5-brominated diphenyl ether results in increased expression of PHGDH protein

PMID:18550172
increases expressionISORGD:619876480464CTD2, 2', 4, 4', 5-brominated diphenyl ether results in increased expression of PHGDH protein

PMID:19954255
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.