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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62221
Species: Mus musculus
RGD Object: Gene
Symbol: Hif1a
Name: hypoxia inducible factor 1, alpha subunit
Acc ID: CHEBI:49798
Term: tetraethylenepentamine
Definition: A polyazaalkane that has formula 189.30192.
Chemical ID: MESH:C034269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hif1amultiple interactionsISOHIF1A (Homo sapiens)6480464CTDCopper Sulfate affects the reaction [tetraethylenepentamine affects the localization of HIF1A protein]; tetraethylenepentamine affects the expression of and affects the localization of HIF1A protein; tetraethylenepentamine inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]; tetraethylenepentamine inhibits the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]PMID:25687434 PMID:26174737
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