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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62191
Species: Mus musculus
RGD Object: Gene
Symbol: Maoa
Name: monoamine oxidase A
Acc ID: CHEBI:18243
Term: dopamine
Definition: Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group.
Chemical ID: MESH:D004298
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Maoaincreases abundanceEXP 6480464CTDMAOA mutant form results in increased abundance of DopaminePMID:11834493
Maoadecreases aminationISOMAOA (Homo sapiens)6480464CTDMAOA protein results in decreased amination of DopaminePMID:26721607
Maoamultiple interactionsISOMAOA (Homo sapiens)6480464CTD3,4-Methylenedioxyamphetamine inhibits the reaction [MAOA protein results in decreased amination of Dopamine]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [MAOA protein results in decreased amination of Dopamine]PMID:26721607
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