Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b4
Name: hydroxysteroid (17-beta) dehydrogenase 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b4decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of HSD17B4 mRNAPMID:30816183 PMID:32528016 PMID:34947998
Hsd17b4increases expressionEXP 6480464CTDbisphenol A results in increased expression of HSD17B4 mRNAPMID:25181051
Hsd17b4multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of HSD17B4 mRNA; [bisphenol A co-treated with Estradiol] results in decreased expression of HSD17B4 mRNAPMID:26496021 PMID:36041667
Hsd17b4decreases expressionISOHSD17B4 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of HSD17B4 proteinPMID:34186270 PMID:37567409
Hsd17b4decreases expressionISOHsd17b4 (Mus musculus)6480464CTDbisphenol A results in decreased expression of HSD17B4 mRNAPMID:33221593
Go Back to source page   Continue to Ontology report