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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621769
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dhcr7
Name: 7-dehydrocholesterol reductase
Acc ID: CHEBI:34680
Term: dipentyl phthalate
Definition: A phthalate ester that is the dipentyl ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C034171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dhcr7decreases expressionEXP 6480464CTDdi-n-pentyl phthalate results in decreased expression of DHCR7 mRNAPMID:22112501 PMID:25055962 PMID:33983380
Dhcr7multiple interactionsEXP 6480464CTD[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of DHCR7 mRNAPMID:25055962
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