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GENE - TERM ANNOTATION REPORT

RGD ID: 621758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp12
Name: caspase 12
Acc ID: GO:0004197
Term: cysteine-type endopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
Definition Source(s): GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:1312922, PANTHER:PTN000048051, UniProtKB:P49662, UniProtKB:P5187813792537GO_CentralPMID:21873635

 
 IEAInterPro:IPR001309, InterPro:IPR002138, InterPro:IPR0023981600115InterProGO_REF:0000002

GO_REF:0000002
 IEAUniProtKB:O08736, ensembl:ENSMUSP000000270091600115EnsemblGO_REF:0000107

GO_REF:0000107
 ISORGD:7314421624291RGD (MGI:MGI:5634893, PMID:12097332)

MGI:MGI:5634893, PMID:12097332
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