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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp12
Name: caspase 12
Acc ID: CHEBI:8207
Term: (+)-pilocarpine
Definition: The (+)-enantiomer of pilocarpine.
Chemical ID: MESH:D010862
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA, [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 protein, Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of CASP12 protein]

PMID:21429313
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.