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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp12
Name: caspase 12
Acc ID: CHEBI:27827
Term: paraoxon
Definition: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.
Chemical ID: MESH:D010261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7314426480464CTDParaoxon results in increased expression of CASP12 protein

PMID:20079824
multiple interactionsISORGD:7314426480464CTDEgtazic Acid inhibits the reaction [Paraoxon results in increased expression of CASP12 protein], Heparin inhibits the reaction [Paraoxon results in increased expression of CASP12 protein], Procaine inhibits the reaction [Paraoxon results in increased expression of CASP12 protein]

PMID:20079824
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.